Binfeng Lu, Ph.D. | Center for Discovery and Innovation NJ   

Lu Lab

Binfeng Lu, Ph.D., is a Member of the Center for Discovery and Innovation and Georgetown Lombardi Comprehensive Cancer Center.

Dr. Lu’s research area includes tumor immunology and cancer immunotherapy. His lab investigates ways to harness T cell-mediated anti-tumor immune responses to treat cancer. His team has performed molecular characterization of tumor-associated Treg cells with the discovery of TIM3+ Treg cells in the tumor immune suppressive microenvironment, established key transcription factors, such as Tbet and Eomes, that regulate tumor-specific memory stem T cells, and ushered in novel cytokine-based cancer immunotherapy based on tissue alarmin cytokines, such as IL-33 and IL-36.

At CDI, the Lu lab studies fundamental molecular mechanisms underpinning anti-tumor immune cellular networks, leveraging data science, cutting-edge immunological techniques, clinically relevant mouse cancer models, and a rich collection of human cancer specimens. The lab’s combined basic and translational research approach will catalyze innovative NextGen immunotherapy for cancer.

Read our interview with Dr. Lu.

Contact the Lab

Mailing Address:
Center for Discovery and Innovation
111 Ideation Way
Nutley, NJ 07110

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