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The ETMR One Registry has partnered with The Children’s Brain Tumor Network (CBTN) for the collection and processing of high-quality ETMR biospecimens and the associated genomic analysis of these tumor samples. Together, we aim to develop ETMR cell lines and transplantable tumor models which will be made available to dedicated researchers from around the globe.
About the CBTN
The Children’s Brain Tumor Network is a collaborative, multi-institutional research program dedicated to the study and treatment of childhood brain tumors. As part of this research effort, the CBTN has developed a network of informatics and data applications which allow researchers from across the world to work together to discover cures. “Innovation through collaboration” is made possible by the CBTN’s state-of-the-art biorepository as well as expertise of leaders in the field of biomedicine.
The CBTTC consists of 16 primary member institutions including: 1) Children’s Hospital of Philadelphia, 2) Seattle Children’s, 3) UPMC Children’s Hospital of Pittsburgh and 4)Ann & Robert H. Lurie Children’s Hospital of Chicago, 5) Benioff Children’s Hospital (UCSF), 6) Stanford University/Lucile Packard Children’s Hospital, 7) Meyer Children’s Hospital Florence Italy, 8) Weill Cornell Medicine Pediatric Brain and Spine Center, 9) Children’s National Health System, 10) Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center, 11) Children’s Hospital of Orange County: CHOC Children’s, 12) University of California Santa Cruz – Treehouse Childhood Cancer Initiative 13) The Beijing Tiantan Hospital Neurosurgery Center (Beijing, China), 14) Genebank (Beijing Genomics Institute – Shenzhen, China), 15) Dayton Children’s Hospital, and 16) The Hudson Institute of Medical Research (Melbourne, Australia).
The operations center of the CBTN is located at Children’s Hospital of Philadelphia and integrates genomic and molecular research, biorepository management and support for the informatics platforms of the CBTN. This infrastructure serves an important role in the CBTN’s ability to provide free and open access to brain tumor data to researchers throughout the world.
The CBTN has established a collaborative multi-institutional tissue and data repository to enable the collection and analysis of the high-quality brain tumor specimens. In addition to specimen data, the repository also links to clinical data to provide a comprehensive snapshot of each unique tumor.
Additionally, the CBTN is committed to the advancement of tissue-based research, allowing researchers throughout the world to access molecular analysis of brain tumor specimens. These initiatives will allow for improvements in therapeutic treatment of patients diagnosed with a brain tumor.